The Chemistry of High Valent Vanadium Oxo Species Interacting with Trisbezenethiolatosilane Ligands

• Main Authors: Gui-Shih Huang, 黃桂施
• Other Authors: Hua-Fen Hsu
• Format: Others
• Language: zh-TW
• Published: 2004
• Online Access: http://ndltd.ncl.edu.tw/handle/778eyc

碩士 === 國立成功大學 === 化學系碩博士班 === 92 === 　　My research has been interested in studying vanadium thiolate chemistry due to its biological significance. Particularly, to understand the protein-tyrosine phosphatase (PTP) which is inhibited by vanadate through the interaction with the Cys residue in the enzyme, I focus my research on the basic chemistry of VO3+ species interacting with thiolato ligands. In the reaction of VO3+ with trisbezenethiolatosilane ligand system, PhSiS3, SiS3 and SiS3’,1 we obtained unexpected divanadium(IV) dioxo complexes, I, II, and III, showing in the following scheme. The formation of compounds I, II, and III indicates that the Si-H/Si-C bonds are cleaved during the reaction. 　　In addition, in order to understand the role of the heterometallic site in the cofactor of nitrogenase, I develop a novel ligand, S3N (IV), which might provide the metal complexes containing the coordination environment similar to that of the heterometallic site of the enzyme.