Enantioseparation of Catecholamines and Structurally Related Compounds by Capillary Zone Electrophoresis Using Sulfated-β-Cyclodextrin as Chiral Selectors.
碩士 === 國立臺灣大學 === 化學研究所 === 92 === In this study, we focus on the enantioseparation of three catecholamines and three structurally related compounds with addition of sulfated cyclodextrins and the optimization of separation. The influences of buffer concentration and temperature on the migration beh...
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ndltd-TW-092NTU050650262016-06-10T04:15:57Z http://ndltd.ncl.edu.tw/handle/89611257204424526558 Enantioseparation of Catecholamines and Structurally Related Compounds by Capillary Zone Electrophoresis Using Sulfated-β-Cyclodextrin as Chiral Selectors. 以硫酸鹽衍生化環糊精為對掌選擇劑對兒茶酚胺類對掌異構物分離之研究 Hsu-Tun Cheng 鄭旭敦 碩士 國立臺灣大學 化學研究所 92 In this study, we focus on the enantioseparation of three catecholamines and three structurally related compounds with addition of sulfated cyclodextrins and the optimization of separation. The influences of buffer concentration and temperature on the migration behavior and enantioseparation of these cationic solutes with addition of sulfated cyclodextrins were investigated. The results indicate that, buffer concentration and temperature play important roles in the enantioseparation of these cationic solutes. In order to understand enantoseparation mechanisms of these cationic solutes also used three kind of neutral cyclodextrins as chiral selectors. Moreover, by mixing two kind of cyclodextrins, we found the reversal of migration order of norephedrine、synephrine and octopamine. The interaction of chiral analytes with chiral selectors was studied through the variation of mobility of norephedrine、synephrine and octopamine. 林敬二 2004 學位論文 ; thesis 88 zh-TW |
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碩士 === 國立臺灣大學 === 化學研究所 === 92 === In this study, we focus on the enantioseparation of three catecholamines and three structurally related compounds with addition of sulfated cyclodextrins and the optimization of separation. The influences of buffer concentration and temperature on the migration behavior and enantioseparation of these cationic solutes with addition of sulfated cyclodextrins were investigated. The results indicate that, buffer concentration and temperature play important roles in the enantioseparation of these cationic solutes. In order to understand enantoseparation mechanisms of these cationic solutes also used three kind of neutral cyclodextrins as chiral selectors. Moreover, by mixing two kind of cyclodextrins, we found the reversal of migration order of norephedrine、synephrine and octopamine. The interaction of chiral analytes with chiral selectors was studied through the variation of mobility of norephedrine、synephrine and octopamine.
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林敬二 |
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林敬二 Hsu-Tun Cheng 鄭旭敦 |
author |
Hsu-Tun Cheng 鄭旭敦 |
spellingShingle |
Hsu-Tun Cheng 鄭旭敦 Enantioseparation of Catecholamines and Structurally Related Compounds by Capillary Zone Electrophoresis Using Sulfated-β-Cyclodextrin as Chiral Selectors. |
author_sort |
Hsu-Tun Cheng |
title |
Enantioseparation of Catecholamines and Structurally Related Compounds by Capillary Zone Electrophoresis Using Sulfated-β-Cyclodextrin as Chiral Selectors. |
title_short |
Enantioseparation of Catecholamines and Structurally Related Compounds by Capillary Zone Electrophoresis Using Sulfated-β-Cyclodextrin as Chiral Selectors. |
title_full |
Enantioseparation of Catecholamines and Structurally Related Compounds by Capillary Zone Electrophoresis Using Sulfated-β-Cyclodextrin as Chiral Selectors. |
title_fullStr |
Enantioseparation of Catecholamines and Structurally Related Compounds by Capillary Zone Electrophoresis Using Sulfated-β-Cyclodextrin as Chiral Selectors. |
title_full_unstemmed |
Enantioseparation of Catecholamines and Structurally Related Compounds by Capillary Zone Electrophoresis Using Sulfated-β-Cyclodextrin as Chiral Selectors. |
title_sort |
enantioseparation of catecholamines and structurally related compounds by capillary zone electrophoresis using sulfated-β-cyclodextrin as chiral selectors. |
publishDate |
2004 |
url |
http://ndltd.ncl.edu.tw/handle/89611257204424526558 |
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