Synthesis and Investigation of Chiral Induction Property of Chiral Secondary Amine:6,7-Dihydro-1,2,3- Trimethoxy-5-Phenyl-bis-Benzo[c]Azepin
碩士 === 國立東華大學 === 化學系 === 93 === This thesis describes about the synthesis and investigation of chiral induction property of chiral secondary amine. Using 3,4,5-trimethoxy-benzaldehyde as starting material, via Suzuki coupling and intramolecular Aza-Wittig reaction obtains the target molecule (A) ea...
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| Format: | Others |
| Language: | zh-TW |
| Published: |
2005
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| Online Access: | http://ndltd.ncl.edu.tw/handle/90825822820446295736 |
| Summary: | 碩士 === 國立東華大學 === 化學系 === 93 === This thesis describes about the synthesis and investigation of chiral induction property of chiral secondary amine. Using 3,4,5-trimethoxy-benzaldehyde as starting material, via Suzuki coupling and intramolecular Aza-Wittig reaction obtains the target molecule (A) easily.
The compound (A) react with carbonyl compound to form the enamine intermediate which can catalyze several asymmetric reactions, such as asymmetric enamine alkylation, aldol reaction, Michael addition and etc.
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