| Summary: | 碩士 === 國立臺灣大學 === 應用力學研究所 === 93 === This study aimed at investigating the physical meaning of VI（Vascularity Index）, using color duplex ultrasound. The renal hemodynamics of canine was used as the testing platform for the quantification of VI using a medical imaging analysis software developed in house. The dynamics power Doppler VI were compared with the pressure waveform and flow waveform measured upstream at the abdominal aorta.
Eleven health dogs aged from nine mouths to five years old, weighted 14- 25 Kg were used in this study. Ultrasonic scanning was focused on the left renal of each dog non-invasively. Both the Doppler spectrum of the renal blood flow and the M-mode image of the abdominal aorta were recorded. Among the test cases, four dogs were selected to differentiate the renal blood vessels at various sections of the kidney; namely interlobar artery（top）、 arcuate artery（middle）、arteriole（below）. Comparing the VI waveforms that obtained from various renal sections with the aortic diameter deformation waveform (which is considered as an alternative pressure waveform) we find the VI waveform from arteriole has a higher correlation statistically than the interlobar artery and the arcuate artery. The corresponding regression analysis were about 0.9371、0.9755、0.8962、0.9037 for these renal VI and the pressure waveform. Dopamine was also used to control the renal blood flow of canine without much alteration of physiological conditions. The blood pressure changed slightly from 86 ± 1 mmHg to 70 ± 2, 72 ± 2 and 72 ± 1 mmHg. Because of the Dopamine affected the renal blood vessels, the regression coefficient between the VI waveform and pressure waveform decreased due to the pharmaceutical action.
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