| Summary: | 碩士 === 大同大學 === 材料工程學系(所) === 93 === Expanded polytetrafluoroethylene (ePTFE) film is a kind of surface hydrophobic materials. To improve the surface hydrophilicity and biocompatibility of ePTFE film, cold plasma treatment, UV graft polymerization and subsequently immobilization of condroitin-6-Sulphate are used in this study.
For the hydrophilic modification of expanded ePTFE films, argon (Ar)
plasma treatment is carried out in order to create active site and free radicals on the surface of ePTFE films, the optimal condition is 50w/10min, 200mtorr and subsequently UV graft polymerization with different hydrophilic monomers and introduce hydrophilic functional groups like C=O, C-O, COOH and NH2. In this study, ePTFE surface can be grafted with different monomers (AAm, AAc, NIPAAM and NVP) successfully. Especially, when ePTFE film is grafted with NVP (80.97mmol, adding APS and TEMED/50min), the hydrophilicity can be improved from 125。to 8。 obviously. But aging effect of surface hydrophilicity modified by plasma treatment and graft polymerization will occur with increasing storage time. Using chemically cross-linking method with cross-linking agent, EDC (5w%) can immobilize the biocompatible polymer, condroitin-6-Sulphate (10wt%) on ePTFE-g-AAc(41.63mmol/20min) films successfully, it was expected to be used as biomaterials.
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