| Summary: | 博士 === 國立中正大學 === 資訊工程所 === 94 === Ultrasound (US) is a valuable adjunct to mammography in breast imaging. Recently, relevant studies have been applied to computer-aided diagnosis (CAD) systems which have demonstrated a promising result for the classification of breast lesions. Although the conventional two-dimensional (2-D) US techniques of the breast at present have been widely used in surgical clinical practice, 2-D images are not enough to transmit the entire characteristics of a solid breast lesion. On the other hand, three-dimensional (3-D) US can fully provide the architecture of breast tumors in all aspects and therefore is capable of offering a more comprehensive way to characterize pathological features. The 3-D CAD systems are expected to be a useful CAD tool for classifying benign and malignant tumors in ultrasound, and can assist physicians to reduce misdiagnosis. In this study, we present our undergoing developments on 3-D breast ultrasound regarding two important properties that are frequently sighted in breast carcinoma, including spiculation, angiogenesis. Our work involves the techniques of how to extract features from the original 3-D images and of how to quantify them. The numerical data was finally related to tumor outcome and showed a good agreement with the delineation of the experts.
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