Spontaneous Oscillations in Hodgkin-Huxley Model
碩士 === 逢甲大學 === 應用數學所 === 94 === Automatic neuron firing is an important and interesting research subject in neuroelectrophysiology. Through the original Hodgkin-Huxley model, we investigate its codimension 1 bifurcations along maximum conductance of sodium channel, maximum conductance of potassium...
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ndltd-TW-094FCU055070152015-12-11T04:04:18Z http://ndltd.ncl.edu.tw/handle/53772765668470166007 Spontaneous Oscillations in Hodgkin-Huxley Model 霍奇金-赫胥黎模型中的自律現象 Ming-Wai Huang 黃民瑋 碩士 逢甲大學 應用數學所 94 Automatic neuron firing is an important and interesting research subject in neuroelectrophysiology. Through the original Hodgkin-Huxley model, we investigate its codimension 1 bifurcations along maximum conductance of sodium channel, maximum conductance of potassium channel, and extracellular potassium concentration. We find that increasing maximum conductance of sodium channel, or decreasing maximum conductance of potassium channel, or increasing extracellular potassium concentration will all cause spontaneous oscillation without any external stimulus current. The effect that increasing extracellular potassium concentration will cause repetitive neuron firing has been verified by experiments, but the effect of changing channel maximum conductance will cause automatic neuron firing is first analyzed in the current paper but not yet verified by experiments. We hope the experiment can be done in the future by using sodium channel activator and potassium channel blocker. Tzyy-Leng Horng 洪 子 倫 2006 學位論文 ; thesis 25 en_US |
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碩士 === 逢甲大學 === 應用數學所 === 94 === Automatic neuron firing is an important and interesting research subject in neuroelectrophysiology. Through the original Hodgkin-Huxley model, we investigate its codimension 1 bifurcations along maximum conductance of sodium channel, maximum conductance of potassium channel, and extracellular potassium concentration. We find that increasing maximum conductance of sodium channel, or decreasing maximum conductance of potassium channel, or increasing extracellular potassium concentration will all cause spontaneous oscillation without any external stimulus current. The effect that increasing extracellular potassium concentration will cause repetitive neuron firing has been verified by experiments, but the effect of changing channel maximum conductance will cause automatic neuron firing is first analyzed in the current paper but not yet verified by experiments. We hope the experiment can be done in the future by using sodium channel activator and potassium channel blocker.
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Tzyy-Leng Horng |
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Tzyy-Leng Horng Ming-Wai Huang 黃民瑋 |
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Ming-Wai Huang 黃民瑋 |
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Ming-Wai Huang 黃民瑋 Spontaneous Oscillations in Hodgkin-Huxley Model |
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Ming-Wai Huang |
title |
Spontaneous Oscillations in Hodgkin-Huxley Model |
title_short |
Spontaneous Oscillations in Hodgkin-Huxley Model |
title_full |
Spontaneous Oscillations in Hodgkin-Huxley Model |
title_fullStr |
Spontaneous Oscillations in Hodgkin-Huxley Model |
title_full_unstemmed |
Spontaneous Oscillations in Hodgkin-Huxley Model |
title_sort |
spontaneous oscillations in hodgkin-huxley model |
publishDate |
2006 |
url |
http://ndltd.ncl.edu.tw/handle/53772765668470166007 |
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