| Summary: | 碩士 === 中興大學 === 材料工程學系所 === 94 === The applications of biomaterials become very important in recent year. In particular, the transportion of drug in the human body is a key issue, and receives a lot of attention in the academic research. Poly(n-isopropylacrylamide) (PNIPAM) gel is a thermally sensitive polymer with excellent response as temperature changes above its lower critical solution temperature (LCST).
In this study, we have prepared nanoscled SiO2 using sol-gel process and then grafted with PNIPAM to prepare PNIPAM/SiO2 nanocomposite. The physical properties of fabricated nanocomposite can be characterized by FTIR, FESEM and TEM, in particular the rheological behavior will be focused.
From these results, the viscosity of PNIPAM/SiO2 nanocomposites with larger particle size of SiO2 is higher than that of smaller particle size of SiO2. The viscosity of PNIPAM/SiO2 nanocomposites is smaller than that of SiO2 nanoparticles.
The viscosity of PNIPAM/SiO2 nanocomposites measured at 37.5˚C in SBF is lower than that at 25˚C. This result indicates the possible polymer chain of PNIPAM become less swollen at higher temperature. Thererefore, the volume fraction of PNIPAM decreases with increasing temperature.
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