Cytotoxic Constituents from Soft Coral Clavularia viridis

• Main Authors: I-wen Lo, 羅宜雯
• Other Authors: Chang-Yih Duh
• Format: Others
• Language: zh-TW
• Published: 2006
• Online Access: http://ndltd.ncl.edu.tw/handle/02402394753687581834

碩士 === 國立中山大學 === 海洋生物科技暨資源學系研究所 === 94 === Seven new steroids, GN70-153E (1), GN70-153F (2), GN70-153I (3), GN70-272F (4), GN70-272I (5), GN70-272L (6), and GN70-272L (7), were isolated from the Formosan soft coral Clavularia viridis by chromatographic separation of the EtOAc layer which was obstained from crude extraction in hexane－Acetone, 100% Acetone, Acetone－MeOH and 100% MeOH then partitioned between EtOAc and H2O. Their structures were determined based on the results of several kinds of spectroscopic analyses and HRESI-MS. Compounds 1-7 exhibited cyctotoxicity against HT-29 and P-388 cell lines in vitro.