High Intensity Focused Ultrasound for Uterine Fibroid Thermal Therapy

• Main Authors: Kuan-Chou Pan, 潘冠州
• Other Authors: Win-Li Lin
• Format: Others
• Language: zh-TW
• Published: 2006
• Online Access: http://ndltd.ncl.edu.tw/handle/51713775644881846983

碩士 === 國立臺灣大學 === 醫學工程學研究所 === 94 === Uterine fibroids are the most common pelvic tumors in women and even it may affect fertility. The interventions for uterine fibroid are myomectomy, hysterectomy and uterine fibroid embolization (UFE). All of these surgical interventions are invasive until the exposure of focused ultrasound surgery. It can provide non-invasive intervention and largely decrease the probability of complications and post-operation bedrid time. Because of less invasive, focused ultrasound has become a promising tool for localized tumor therapy. Clinical tests, however, have shown that the main problems are long treatment time and skin burn which the ultrasound propagates through. In this study, based on a MRI compatible ultrasound treatment system, we carry out a simplified two - medium simulation for uterine fibroid intervention. The system is composed of four transducers which are oriented in an incident angle of 30 degrees to the skin – water interface to heat the target from four separate paths. Compared with single path stacking treatment which is used commonly on the present, using the system could disperse absorbed power in the skin under the condition of the same total power output. Soaking skin behind the target region in cooling degased water during operation aims to prevent over- heating in the skin. If the two transducers of the diagonal line operate simultaneously, it could lessen the treatment time. Compared with simulation results of multiple path treatment of our system and single path stacking treatment, multiple path treatment could provide precise heating intervention in a shorter time and diminish temperature elevation of the skin.