To investigate the association between B-vitamins status (folate, vitamin B-12 and B-6) and hyperhomocysteinemia in healthy adult population
碩士 === 中山醫學大學 === 營養學研究所 === 95 === To provide more information on B-vitamins (folate, vitamin B-12 and vitamin B-6) in relation to fasting and post methionine loading (PML) homocysteine (Hcy) concentrations, we examined folate, vitamin B-12, B-6 and PML homocysteine in normo-homocysteinemia (N-Hcy,...
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ndltd-TW-095CSMU55130082015-10-28T04:07:06Z http://ndltd.ncl.edu.tw/handle/74287761365286342077 To investigate the association between B-vitamins status (folate, vitamin B-12 and B-6) and hyperhomocysteinemia in healthy adult population 探討健康成年人B-維生素 (葉酸、維生素B-12及B-6) 的營養狀況與高同半胱胺酸血症的相關性 Fang-Pei 陳芳霈 碩士 中山醫學大學 營養學研究所 95 To provide more information on B-vitamins (folate, vitamin B-12 and vitamin B-6) in relation to fasting and post methionine loading (PML) homocysteine (Hcy) concentrations, we examined folate, vitamin B-12, B-6 and PML homocysteine in normo-homocysteinemia (N-Hcy, <12 mmol/L) and hyperhomocysteinemia (H-Hcy, ³ 12mmol/L) adults. One hundred and ninety-nine 31-50 years old healthy men (n = 100) and women (n = 99) were recruited from the community and assigned to either the N-Hcy (n = 145) or H-Hcy (n = 54) group. Fasting and PML Hcy, hematological parameters were measured. Fasting and PML Hcy of women in N-Hcy were significant lower than men. Subjects in the N-Hcy group had significantly higher serum folate and vitamin B-12 and lower PML homocysteine concentrations than H-Hcy subjects did. There was no significant difference in vitamin B-6 values between groups. However, serum folate (β = -0.153, p = 0.002) was strongly inversely associated with fasting plasma homocysteine; vitamin B-12 was inversely correlated with PML homocysteine (β = -0.002, p = 0.027). High serum folate concentration (OR = 0.784, p < 0.001) significantly decreased the risk of fasting hyperhomoycsteinemia. High serum folate concentration might be a protective factor of hyperhomocysteinemia in the healthy adult population. 黃怡嘉 2007 學位論文 ; thesis 81 zh-TW |
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碩士 === 中山醫學大學 === 營養學研究所 === 95 === To provide more information on B-vitamins (folate, vitamin B-12 and vitamin B-6) in relation to fasting and post methionine loading (PML) homocysteine (Hcy) concentrations, we examined folate, vitamin B-12, B-6 and PML homocysteine in normo-homocysteinemia (N-Hcy, <12 mmol/L) and hyperhomocysteinemia (H-Hcy, ³ 12mmol/L) adults. One hundred and ninety-nine 31-50 years old healthy men (n = 100) and women (n = 99) were recruited from the community and assigned to either the N-Hcy (n = 145) or H-Hcy (n = 54) group. Fasting and PML Hcy, hematological parameters were measured. Fasting and PML Hcy of women in N-Hcy were significant lower than men. Subjects in the N-Hcy group had significantly higher serum folate and vitamin B-12 and lower PML homocysteine concentrations than H-Hcy subjects did. There was no significant difference in vitamin B-6 values between groups. However, serum folate (β = -0.153, p = 0.002) was strongly inversely associated with fasting plasma homocysteine; vitamin B-12 was inversely correlated with PML homocysteine (β = -0.002, p = 0.027). High serum folate concentration (OR = 0.784, p < 0.001) significantly decreased the risk of fasting hyperhomoycsteinemia. High serum folate concentration might be a protective factor of hyperhomocysteinemia in the healthy adult population.
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author2 |
黃怡嘉 |
author_facet |
黃怡嘉 Fang-Pei 陳芳霈 |
author |
Fang-Pei 陳芳霈 |
spellingShingle |
Fang-Pei 陳芳霈 To investigate the association between B-vitamins status (folate, vitamin B-12 and B-6) and hyperhomocysteinemia in healthy adult population |
author_sort |
Fang-Pei |
title |
To investigate the association between B-vitamins status (folate, vitamin B-12 and B-6) and hyperhomocysteinemia in healthy adult population |
title_short |
To investigate the association between B-vitamins status (folate, vitamin B-12 and B-6) and hyperhomocysteinemia in healthy adult population |
title_full |
To investigate the association between B-vitamins status (folate, vitamin B-12 and B-6) and hyperhomocysteinemia in healthy adult population |
title_fullStr |
To investigate the association between B-vitamins status (folate, vitamin B-12 and B-6) and hyperhomocysteinemia in healthy adult population |
title_full_unstemmed |
To investigate the association between B-vitamins status (folate, vitamin B-12 and B-6) and hyperhomocysteinemia in healthy adult population |
title_sort |
to investigate the association between b-vitamins status (folate, vitamin b-12 and b-6) and hyperhomocysteinemia in healthy adult population |
publishDate |
2007 |
url |
http://ndltd.ncl.edu.tw/handle/74287761365286342077 |
work_keys_str_mv |
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