| Summary: | 碩士 === 朝陽科技大學 === 應用化學系碩士班 === 95 === Polylactic acid is the lactic acid from micro-organism fermented plant starch with polymerization reaction of the relevant catalyst. In view that the plastic products from petrochemistry could not be dissolved by the micro-organisms in the natural environment, massive pollution of the environment has therefore resulted today. Usage of the starch based polylactic acid may help resolve the pollution problem caused by the usage of plastic products because the physical and chemical characteristics of the polylactic acid are similar to those of the plastic products, making it possible for the former to substitute the latter. Furthermore, polylactic acid is one kind of biodegradable plastics. After the degradation, it becomes organic fertilizer which is good nutrition for the plants. Its basic material, or the starch, is one kind of natural resources that could be continually and repeatedly obtained. Hence, it is apparent that biodegradable polylactic acid is more environmentally friendly compared to the traditional plastic products. Additionally, besides polylactic acid’s excellent contribution from an environmental protection perspective, it is the basic material for one new kind of biocompatible polymer (medical grade polymer) which is ingestible by human metabolism without generating toxin during the process. Hence, it could be used as the basic material to produce suture for use in medical surgeries, medical bone stabilizing board, material for controlling drug release, etc. With some special control, polylactic acid can be programmed to produce polylactic particles of varying custom-made sizes. Polylactic particles can be used to hood or enclose medicine. Based on the fact that different sizes of the polylactic particles can be ingested by different parts of the human body or, through the usage of the “percolation hold up principle”, specific medicine could be delivered to the ailing part of the human body, thereby minimizing the pharmaceutical impact to the healthy parts of the human body. Polylactic acid, therefore, plays an important role in the Targeted Drug Delivery System (TDDS).
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