| Summary: | 碩士 === 國立成功大學 === 公共衛生研究所 === 95 === Background：Rotavirus is the leading cause of
serve gastroenteritis and
dehydration among children ＜5 years
old. The rotavirus infection is
common in both developed and
developing nations among children,
which caused substantial diseases
and economic burden. In order to
assess the potential value of
rotavirus vaccines, we must
understand the diseases and economic
burden caused by rotavirus annually
in Taiwan.
Objective：To estimate the economic burden of
hospitalization caused by rotavirus
for future vaccination strategies in
Taiwan.
Method：The study objectives were 2600
hospitalized diarrhea children who under
five years old at four hospitals
(National Taiwan University Hospital,
Taipei Veteran General Hospital,
Taichung Veteran General Hospital and
Kaohsiung Veteran General Hospital) from
1 April, 2001 to 31 March, 2003 in
Taiwan. The case report form these four
hospitals was used to calculate the
medical costs（including the costs of
NHI and copayment）and self-reported
questionnaires was used to estimate the
other related costs（travel costs, lost
wages, other medical costs and other
related costs）and to calculate the
social costs, private costs, direct
costs and indirect costs. National
Health Insurance Research Database was
used to estimate the number of
hospitalized rotavirus infection
children cased by diarrhea during 2001
and 2003 in Taiwan. Then the result of
2600 study objectives will be
generalized to the nation.
Result：Rotavirus causes 12,000~15,000
hospitalizations per year among children
＜5 years old. On average, the social
cost was NT $30,166 per case, the
private cost was NT $ 16,806 per case,
the direct cost was NT $23,681 per case,
and the indirect cost was NT $ 6,485 per
case. The total annual social cost was
about NT $360~460 million, the total
annual private cost was about NT
$200~260 million, the total annual
direct cost was about NT $ 280~360
million, and the total annual indirect
cost was about NT $76~100 million. On
average, each family spent NT $10,321
once their child was hospitalized with
rotavirus infection.
Conclusion：Rotavirus caused substantial
diseases and economic burden in
Taiwan. To prevent the rotavirus
infection, a safe and effective
vaccine is needed.
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