| Summary: | 碩士 === 國立屏東科技大學 === 獸醫學系 === 95 === The effect of supplementation with a product derived from Cordyceps militaris fed in daily water and feed on broiler of immunity response and body weight were investigated. Test broiler groups were administered C. militaris in daily water 15, 30 and 60 mg/kg BW/day, respectively. The results showed that body weight for 21 days old was 793±32.8 g in control group, 808±54.3 g ( low dosage ), 832±45.7 g ( middle dosage ) and 898±29.7 g ( high dosage ), in each test group for 35 days old chickens, 1467.5±75.2 g in control group, in each test group were observed. 1658±70.3 g, 1732.5±85.4 g and 1905.5±88.2 g. Moreover, the results showed that body weight for 42 days old was 1682.5±78.5 g in control group, and in each test groups were 1918.5±125.1 g, 2012.5±89.4 g and 2195±99.8 g, respectively. The results showed statistically significant ( P＜0.05 ). In sum, a product of C. militaris mixed with water and gave to broiler daily. The results revealed that body weight and feed efficiency were enhanced in each test groups when compared to the control group. Those broilers were vaccinated with newcastle disease virus ( NDV ) and infectious bronchitis virus ( IBV ) at four days old, and infectious bursal disease virus ( IBDV ) at age of 21th day. Those antibody were analyzed by hemagglutinin inhibit ( HI ) test and enzyme-linked immunosorbent assay ( ELISA ) for 1, 7, 14, 21, 28, 35 and 42 days old chickens, respectively. The results revealed that all antibody titer couldn’t be enhanced, in each test group, but decrease at 14th day of age. When their feed supplemented with C. militaris. However, all chickens in high dosage group ( 1000 ppm ) were survival after challenged with high virulent NDV. The control group showed only 0％ surviving rate. Therefore, feed added with C. militaris at concentration of 1000 ppm could protect chickens against NDV infection.
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