| Summary: | 碩士 === 國立台北護理學院 === 醫護管理研究所 === 95 === ABSTRACT
Background: Gastric cancer is one of the most common cancers in Taiwan. Pervious studies of gastric cancer had focused on the pathogenesis, risk factors, prevention and treatments of gastric cancer, but few had tried to study the issues caused by long-term comprehensive prognosis factors. Furthermore, many studies had demonstrated the important prognostic factors of gastric cancer, but there were rarely researches about the long-term examinations of operative patients.
Objective: This study aimed to investigate demographic, clinical, pathological variables and period groups associated with survival status of gastric cancer patients.
Data source: From 1974 to 2003, the hospital data of 1,240 gastric cancer patients concerning surgical treatment, pathological diagnosis and outcome were collected.
Methods: Retrospective analysis of the results was made, five year survival rates were calculated by Kaplan-Meier method and univariate analysis and multiple factors comparison were done through Log-rank test and Cox proportional hazard model.
Results: The prognostic factors which affecting gastric cancer patients were age, clinical and pathological variables. Single factor analysis indicated that period group was significantly influential factors for the prognosis of patients. With other prognosis factors being controlled, five year survival rate for the gastric cancer patients undergoing surgeries during 1994 to 2003 was better than that of the gastric cancer patients during 1974 to 1983. However, there was no significance between the group of 1974 to 1983 and 1984 to 1993.
Discussion: Using multi-institutional comparison or studying supportive care may add more information about patients and hospitals which will aid prognosis improvement.
|
|---|
