Design and Fabrication of A Novel Cell-chip with Local Drug Delivery Function

碩士 === 國立清華大學 === 工程與系統科學系 === 95 === In this study, we develop a novel nano drug delivery system for single-cell chip, which includes cell culture cavities and nano fluid delivery channels for localized drug delivery onto single cell. In order to clear the observation path for optical microscope,...

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Main Authors: Chiu Hsin-Chih, 邱新智
Other Authors: 曾繁根
Format: Others
Language:zh-TW
Published: 2007
Online Access:http://ndltd.ncl.edu.tw/handle/40086224807789806806
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spelling ndltd-TW-095NTHU55930652015-10-13T16:51:15Z http://ndltd.ncl.edu.tw/handle/40086224807789806806 Design and Fabrication of A Novel Cell-chip with Local Drug Delivery Function 具定點藥物輸送功能之新型細胞晶片設計與製作 Chiu Hsin-Chih 邱新智 碩士 國立清華大學 工程與系統科學系 95 In this study, we develop a novel nano drug delivery system for single-cell chip, which includes cell culture cavities and nano fluid delivery channels for localized drug delivery onto single cell. In order to clear the observation path for optical microscope, single-cell was incubated on a transparent silicon nitride membrane, and drugs were delivered surrounding the cell from the nano channels underneath the membrane without the influence of observation. Chip fabrication and flow testing in the nano channel has been successfully carried out, and demonstrated a promising result on localized drug delivery for single cells. 曾繁根 2007 學位論文 ; thesis 65 zh-TW
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language zh-TW
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description 碩士 === 國立清華大學 === 工程與系統科學系 === 95 === In this study, we develop a novel nano drug delivery system for single-cell chip, which includes cell culture cavities and nano fluid delivery channels for localized drug delivery onto single cell. In order to clear the observation path for optical microscope, single-cell was incubated on a transparent silicon nitride membrane, and drugs were delivered surrounding the cell from the nano channels underneath the membrane without the influence of observation. Chip fabrication and flow testing in the nano channel has been successfully carried out, and demonstrated a promising result on localized drug delivery for single cells.
author2 曾繁根
author_facet 曾繁根
Chiu Hsin-Chih
邱新智
author Chiu Hsin-Chih
邱新智
spellingShingle Chiu Hsin-Chih
邱新智
Design and Fabrication of A Novel Cell-chip with Local Drug Delivery Function
author_sort Chiu Hsin-Chih
title Design and Fabrication of A Novel Cell-chip with Local Drug Delivery Function
title_short Design and Fabrication of A Novel Cell-chip with Local Drug Delivery Function
title_full Design and Fabrication of A Novel Cell-chip with Local Drug Delivery Function
title_fullStr Design and Fabrication of A Novel Cell-chip with Local Drug Delivery Function
title_full_unstemmed Design and Fabrication of A Novel Cell-chip with Local Drug Delivery Function
title_sort design and fabrication of a novel cell-chip with local drug delivery function
publishDate 2007
url http://ndltd.ncl.edu.tw/handle/40086224807789806806
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