Properties of surface modification on indium-tin-oxide glasses by layer by layer

• Main Authors: Yu Li Chen, 陳郁莉
• Other Authors: J.M. Yang
• Format: Others
• Published: 2008
• Online Access: http://ndltd.ncl.edu.tw/handle/24921941646189563357

碩士 === 長庚大學 === 化工與材料工程研究所 === 96 === Abstract Indium-tin-oxide substrate (ITO) is modified by heparin and chitosan that is used for layer-by-layer method. The physiochemical characteristics of the ITO and modified samples were determined by weight change, ATR-FTIR, protein adsorption, AFM, CV and stained test. Furthermore, cell culture test and cell morphology were evaluated the biocompatibility of ITO and modified samples. According to the result of weight change test, it was found that ITO weight decreased with reactive time of NaOH solution. The contact angle and protein adsorption both showed a decreasing trend due to the carboxyl group on ITO surface. In addition to, the result of ATR-FTIR could confirm that the surface of modified ITO exist heparin and chitosan. The 3D pictures of AFM showed that the surface of ITO was becoming roughness to modify. The CV diagram would determine that the surface of modified ITO affect the electrical property. When 3T3 fibroblasts were cultured on these substrates, the adhering ability on these substrates is as well as TCPS. But the growth numbers of cells were less than TCPS. It could demonstrate that these substrates were biocompatibility.