| Summary: | 碩士 === 長庚大學 === 護理學研究所 === 96 === Hot flashes is a common but ignored symptom during the period of treatments in women with breast cancer. It has impact on physiological or psychological status. The purpose of the study was to understand the prevalence of hot flashes and its relationship with sleep disturbance among women with breast cancer from pre-surgery to one year after surgery. In order to discuss the effect of different treatments on relationship of hot flashes and sleep disturbance, patients were divided into two groups: receive chemotherapy alone and chemotherapy combined hormonal therapy. Patients were assessed at baseline (pre-operation), mid-chemotherapy, end-chemotherapy and 1 year post-operation. Data were analyzed with descriptive statistics, Chi-Squared test and Hierarchical Linear Model (HLM).
A total of 142 patients were selected from a large study. Prevalence of hot flashes in two groups were highest at post-operation and lowest at mid-chemotherapy; however no significant difference was found between two groups. The severity and distress of hot flashes in two groups were also not different. The sleep disturbance of patients in two groups were both highest at mid-chemotherapy and lowest at post-operation. Sleep disturbance were decrease significantly over time, moreover presence of hot flashes was associated with higher sleep disturbance. Treatment type did not influence the effect of sleep disturbance over the time. After adjusted for age, treatment, pain, depression, fatigue, performance and the severity of menopausal symptoms, patients who got hot flashes frequently were more likely to have decreased sleep quality over time.
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