Inhibitory Effect of Chinese Herb Extract on Streptococcus mutans of Caries

• Main Authors: Ming-Yi Chang, 張銘毅
• Other Authors: K-C.Tzeng
• Format: Others
• Language: zh-TW
• Published: 2008
• Online Access: http://ndltd.ncl.edu.tw/handle/44836544828343738380

碩士 === 國立中興大學 === 生命科學院碩士在職專班 === 96 === Abstract Caries is one of the most popular oral disease,Streptococcus mutans is the major pathogenic bacteria involved in caries,that can produce sticky polysaccharides attaching on tooth surface and forming dental plaque. It also decomposites carbohydrates into acid compounds that will destroy dentin, enamel and reverts in forming caries .Therefore, reducing the number of S. mutans in oral cavity can prevent this event . Chinese herb of Scutellaria baicalensis Georgi ,Houttuynia cordata Thunb, Lygodiumjaponicum (Thumb.)Sw,Eriobotrya japanica(Thunb.) Lindl, Vigna umbellate, Artemisia capillaris Thunb and Asparagus cochinchinensis (Lour.) Merr. are used in this study.Dry materials are extracted with alcohol and water (1/1),and condensed rotary vaccum evaporator . Bilayer agar method are used to examine the bacteriocidal effect of extracts on the S. mutans lines of 10793,15256,15258,5252and 7691.The results show that inhibition zone of S. mutans in 10793.15256 and 15258 of S. mutans. inhibition zone of S. mutans 15256 in Scutellaria baicalensis Georgi is 0.21 cm width，and Lygodiumjaponicum(Thumb.)Sw. is the best 0.66 cm respectively. Moreover,4 times condense extract of Scutellaria baicalensis Georgi , the clearance of zone width may expand to 0.46 cm.Besides,commercial tooth powder In different test with YA-DR-AN and CHI-KO-KAN, are test for the best dilute concentration of 2. 4. 8 folds. The extract of Lygodium japonicum (Thumb.)Sw has inhibitory effect to S. mutans better than Scutellaria baicalensis Georgi . The agility get lost soon after treatment for 2 minutes. The inhibitory ability of Chinese herb extract decrease after infiltration and heat by autoclave . Keyword：caries. Streptococcus mutans. Chinese herb . extract. YA-DR-AN. CHI-KO-KAN