Dynamical correlation in proteins
碩士 === 國立交通大學 === 生物科技系所 === 96 === There are residues in proteins not directly bind to ligand, but they can dramatically affect the binding affinity(tenfold or higher)between protein and ligand. These residues called hot spot residues which can be detected by alanine scanning mutagenesis in protein...
Main Authors: | Shian-Lei Ho, 何仙蕾 |
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Other Authors: | Jenn-Kang Hwang |
Format: | Others |
Language: | en_US |
Published: |
2008
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Online Access: | http://ndltd.ncl.edu.tw/handle/47874162911489211925 |
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