Heterologous Expression and Functional Analysis of Helicobacter pylori Neutrophil-Activating Protein
碩士 === 國立清華大學 === 分子與細胞生物研究所 === 96 === 胃幽門螺旋桿菌是引發胃炎、消化性潰瘍,以及胃癌的主要致病菌。而胃幽門螺旋桿菌嗜中性白血球激活蛋白是胃幽門螺旋桿菌的重要致病因子。許多研究指出胃幽門螺旋桿菌嗜中性白血球激活蛋白具有活化先天性與後天性免疫細胞的能力。為了取得足夠的胃幽門螺旋桿菌嗜中性白血球激活蛋白,大腸桿菌與枯草桿菌已被用來表現重組胃幽門螺旋桿菌嗜中性白血球激活蛋白。然而,大腸桿菌中的內毒素可能會干擾胃幽門螺旋桿菌嗜中性白血球激活蛋白所誘發的免疫反應。關於枯草桿菌表現系統的建立也不甚清楚。因此,在本篇論文的第一部分裡,已建立一個有效的方法,藉此從大腸桿...
Main Authors: | Chung-An Wang, 王仲安 |
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Other Authors: | Hua-Wen Fu |
Format: | Others |
Language: | en_US |
Published: |
2008
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Online Access: | http://ndltd.ncl.edu.tw/handle/69557574417333011551 |
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