| Summary: | 碩士 === 國立陽明大學 === 物理治療暨輔助科技學系 === 96 === Background and purposes：Aerobic training can improve not only aerobic capacity but also symptoms and survival rate in patients with heart failure (CHF). The purposes of our study will test the effects of exercise training on aerobic capacity, heart rate, blood pressure, cardiac output, body composition, serum lipid and NT-proBNP (aminoterminal fragment brain natriuretic peptide prohormone) in CHF patients, and examine the potential benefit of changes over time.
Methods: The quei-experimental design and purposive sampling were fulfilled in this study. The samples consisted of 13 eligible cases with heart failure. Seven of them completed 12-week exercise program ( 30 minutes a day, 3 days a week, at 60 % peak oxygen uptake (VO2peak)). Every 4 weeks training, heart rate, blood pressure, body composition, serum lipid and NT-proBNP were measured after an overnight fast. Besides, VO2peak and cardiac output were measured at pre-training and post-training.
Descriptive analysis were performed first to understand the characteristics of the samples of all pre-training parameters; pair t test was used to examined the differences between pre-training and post-training among patients, further, pair t test was simultaneously used to determinate the time effects of exercise training on all parameters.
Results：After 12-week exercise training program, seven cases completed the process. The results indicate that the parameters of cardiopulmonary capacity were all significant improved. The VO2peak was improved from 20.30±5.30 to 22.49±4.36 ml/kg/min (p=.002). The duration of exercise testing was improved from 7.88±2.03 to 9.92± 2.95 minutes (p=.0001). The maximal metabolic equivalent (MET) was improved from 5.76±1.55 to 6.37±1.31 METs (p=.0001). The maximal work load was improved from 220.43±76.39 to 276.57.43±75.91Watt (W)(p=.029) Among the results of study, the static heart rate was decreased from 71.6±7.5 beat/min to 65.6±8.4 beat/min (p=.045) after 8-week training. Although it was not significant, diastolic pressure and systolic pressure were improved over training time. Meanwhile, after 12-week training, static cardiac output was not significant changed, but dynamic cardiac output was significant improved (increased 2.37ml/min p=.015) Furthermore, body mass index (BMI), waist-to-hip ratio, and triglyceride were significantly improved ( p<.05). However, total cholesterol and NT-proBNP did not decreased significantly. But the more time of exercise training they received, the more they improved.
Conclusion：It is concluded that aerobic exercise training could improve cardiopulmonary capacity, static heart rate, blood pressure, cardiac output, body composition, serum lipid and NT-proBNP in heart failure patients. The results also proved the effects of aerobic exercise for heart failure patients could be accumulated over time. Therefore, provide precise exercise prescriptions and educate them how to do the adequate aerobic exercise training are very important to patients with hear failure.
|
|---|
