| Summary: | 碩士 === 國立成功大學 === 護理學系碩博士班 === 97 === Background: People living with HIV who was faced with HIV disease progression and HIV related stress that may trigger off depressive symptom. However, depressive symptoms are difficult to detect. The depressive symptoms of patients with HIV might affect their quality of life, decrease adherence to antiretroviral therapy, and further exacerbate disease progression.
Objective: The study purposes were to examine the relationships among HIV disease progress, perceived stress, social stigma, and depressive symptoms and to investigate the predictors of depressive and major depressive symptoms among patients with HIV.
Method: Study subjects were recruited from infectious disease outpatient clinics in a university hospital in southern Taiwan. Data was collected including chart reviews and four self-administered questionnaires: Beck Depression Inventory, Perceived Stress Scale, Multidimensional Scale of Perceived Social Support, and Social Impact Scale.
Results: The prevalence rate of depressive symptoms and major depressive symptoms among patients with HIV were 42.5% and 15.6%, respectively. Multiple regression analysis indicated that CD4 cell counts, perceived stress, and social stigma were associated with depressive symptoms, accounting for 46% of the variance in depressive symptoms. The independent predictors associated with increased odds of major depressive symptoms were perceived stress (OR:1.24, 95% CI:1.10-1.39) and social stigma (OR:1.47, 95% CI:1.09-1.97).
Conclusion: People living with HIV were prone to major depressive symptoms which were affected by perceived stress and social stigma. Perceived stress and social stigma could provide reference for further intervention to prevent major depressive symptoms among people living with HIV.
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