Modeling and Operation Strategy Analysis of Pichia stipitis Ethanol Fermentation Using Cybernetic Model

• Main Authors: Tzu-Hsing Wang, 王子興
• Other Authors: I-Lung Chien
• Format: Others
• Language: zh-TW
• Published: 2009
• Online Access: http://ndltd.ncl.edu.tw/handle/10975634666454999506

碩士 === 國立臺灣科技大學 === 化學工程系 === 97 === In this research, the cybernetic model is used to simulate the Pichia stipitis fermentation processfor the mixture of glucose and xylose. In order to fit batch experiment data, the growth rate expression of cybernetic model of costois form is used instead of Monod form. The experimental data from batch fermentation process is used to obtain the model parameter. This model is then used to simulate continuous fermentation processes. The result shows the competition between growth enzyme and low-maintenance enzyme will exhibit some stable oscillations in low dilution rate of glucose/xylose substrate. The optimization tool used in this research is Genetic Algorithm.This optimization method is used to maximize the ethanol productivity and to find the optimal operation conditions for different substrate conceration ratio and different volume ratio in fed-batch operation. The result shows a mixture with 75% xylose and 25% glucose can obtain maximum ethanol productivity.