Part 1:New Highly Selective Colorimetric and Fluorescent Chemosensors for Mercury IonPart 2:The Renal Toxicity of Tetrandrine
碩士 === 靜宜大學 === 應用化學研究所 === 97 === Part 1:New Highly Selective Colorimetric and Fluorescent chemosensors for Mercury Ion Three new chemodosimeters were prepared, they are 1-(4-(Trifluoro methyl) phenyl)-3-(pyren-1-yl) thiourea (1)、1-(4-nitrophenyl)-3-(pyren- 1-yl) thiourea (2)、1-(4-methoxyphenyl)-3-...
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ndltd-TW-097PU0055000182019-05-15T20:07:00Z http://ndltd.ncl.edu.tw/handle/s8sbqb Part 1:New Highly Selective Colorimetric and Fluorescent Chemosensors for Mercury IonPart 2:The Renal Toxicity of Tetrandrine 一、研發能利用肉眼和螢光偵測汞的新化學感測劑 二、粉防己鹼對腎毒性之研究 Chiung-Cheng Lin 林瓊錚 碩士 靜宜大學 應用化學研究所 97 Part 1:New Highly Selective Colorimetric and Fluorescent chemosensors for Mercury Ion Three new chemodosimeters were prepared, they are 1-(4-(Trifluoro methyl) phenyl)-3-(pyren-1-yl) thiourea (1)、1-(4-nitrophenyl)-3-(pyren- 1-yl) thiourea (2)、1-(4-methoxyphenyl)-3-(pyren-1-yl) thiourea (3), respectively. Their chromogenic and fluorogenic chemodosimetric behaviors toward various metal cations were investigated. Receptors (1) to (3) show exclusively response toward Hg2+ ions and also distinguish Hg2+ from other metal cations by color changes. Among them, receptor (1) also exhibited a pronounced Hg2+-induced fluorescence enhancement and a wide pH span (4.0- 10.0). Thus, the receptor (1) can be used as a colori metric and fluorescent chemodosimeter for determination of Hg2+ ion. Part 2:The Renal Toxicity of Tetrandrine Fangji mainly includes Stephania tetrandra S. Mooret and Aristolochia fangchi. Generally we are called Fangji and Guang Fenji separately. However, their chemical constituents are different. The main active chemical constituents in the roots of S. tetrandra are the alkaloids tetrandrine while aristolochic acid is the major bioactive constituent of the root of A. fangchi. We known Guang Fangji has the toxicity and the carcinogenicity to the normal hepatic and renal cell or the organization. The plant root''s shape and name are similar, therefore it is easy to misused. The plant Stephania tetrandra S. Mooret was used in ancient China. It has been clinically used to treat patients with inflammation, hypertension and it also has anti-tumor/growth effect. Previous report that describe tetrandrine have certain toxicity, therefore we intend to study tetrandrine toxicity in vitro and in vivo. Yao-Pin Yen 顏耀平 2009 學位論文 ; thesis 172 zh-TW |
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碩士 === 靜宜大學 === 應用化學研究所 === 97 === Part 1:New Highly Selective Colorimetric and Fluorescent
chemosensors for Mercury Ion
Three new chemodosimeters were prepared, they are 1-(4-(Trifluoro methyl) phenyl)-3-(pyren-1-yl) thiourea (1)、1-(4-nitrophenyl)-3-(pyren- 1-yl) thiourea (2)、1-(4-methoxyphenyl)-3-(pyren-1-yl) thiourea (3), respectively. Their chromogenic and fluorogenic chemodosimetric behaviors toward various metal cations were investigated. Receptors (1) to (3) show exclusively response toward Hg2+ ions and also distinguish Hg2+ from other metal cations by color changes. Among them, receptor (1) also exhibited a pronounced Hg2+-induced fluorescence enhancement and a wide pH span (4.0- 10.0). Thus, the receptor (1) can be used as a colori metric and fluorescent chemodosimeter for determination of Hg2+ ion.
Part 2:The Renal Toxicity of Tetrandrine
Fangji mainly includes Stephania tetrandra S. Mooret and Aristolochia fangchi. Generally we are called Fangji and Guang Fenji separately. However, their chemical constituents are different. The main active chemical constituents in the roots of S. tetrandra are the alkaloids tetrandrine while aristolochic acid is the major bioactive constituent of the root of A. fangchi. We known Guang Fangji has the toxicity and the carcinogenicity to the normal hepatic and renal cell or the organization. The plant root''s shape and name are similar, therefore it is easy to misused. The plant Stephania tetrandra S. Mooret was used in ancient China. It has been clinically used to treat patients with inflammation, hypertension and it also has anti-tumor/growth effect. Previous report that describe tetrandrine have certain toxicity, therefore we intend to study tetrandrine toxicity in vitro and in vivo.
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author2 |
Yao-Pin Yen |
author_facet |
Yao-Pin Yen Chiung-Cheng Lin 林瓊錚 |
author |
Chiung-Cheng Lin 林瓊錚 |
spellingShingle |
Chiung-Cheng Lin 林瓊錚 Part 1:New Highly Selective Colorimetric and Fluorescent Chemosensors for Mercury IonPart 2:The Renal Toxicity of Tetrandrine |
author_sort |
Chiung-Cheng Lin |
title |
Part 1:New Highly Selective Colorimetric and Fluorescent Chemosensors for Mercury IonPart 2:The Renal Toxicity of Tetrandrine |
title_short |
Part 1:New Highly Selective Colorimetric and Fluorescent Chemosensors for Mercury IonPart 2:The Renal Toxicity of Tetrandrine |
title_full |
Part 1:New Highly Selective Colorimetric and Fluorescent Chemosensors for Mercury IonPart 2:The Renal Toxicity of Tetrandrine |
title_fullStr |
Part 1:New Highly Selective Colorimetric and Fluorescent Chemosensors for Mercury IonPart 2:The Renal Toxicity of Tetrandrine |
title_full_unstemmed |
Part 1:New Highly Selective Colorimetric and Fluorescent Chemosensors for Mercury IonPart 2:The Renal Toxicity of Tetrandrine |
title_sort |
part 1:new highly selective colorimetric and fluorescent chemosensors for mercury ionpart 2:the renal toxicity of tetrandrine |
publishDate |
2009 |
url |
http://ndltd.ncl.edu.tw/handle/s8sbqb |
work_keys_str_mv |
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