Oxidative Stress and Its Consequence in Human Cells Harboring MERRF-specific A8344G Mutation of mtDNA — Emphasis on Oxidative Damage to Enzymes Containing Fe-S Cluster

博士 === 國立陽明大學 === 生化暨分子生物研究所 === 97 === Increase in the production of reactive oxygen species (ROS) and decrease in mitochondrial protein synthesis have been implicated in the pathogenesis of myoclonic epilepsy with ragged-red fibers (MERRF) syndrome, which is mainly caused by the A8344G mutation at...

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Bibliographic Details
Main Authors: Yi-Shing Ma, 馬逸興
Other Authors: Yau-Huei Wei
Format: Others
Language:en_US
Published: 2009
Online Access:http://ndltd.ncl.edu.tw/handle/a2w222

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