Relations Between Pain Cry and Heart Rate Variability in Healthy Neonates

• Main Authors: Yu-Chu Hsiao, 蕭羽筑
• Other Authors: Tsair Kao
• Format: Others
• Language: zh-TW
• Published: 2009
• Online Access: http://ndltd.ncl.edu.tw/handle/m2998f

碩士 === 國立陽明大學 === 醫學工程研究所 === 97 === Our research tried to discuss the change in neonate’s HRV during injection and the correlations between the pain cry and HRV parameters.We collected ECG data for at least 5 minutes from the neonate in rest status and ended collection 5 minutes after injection. In the meanwhile, we recorded the cry sound due to injection. We used the voice processing software to analyze fundamental frequency and first formant in the cry sound. For observing the change in physiology, we evaluated representative parameters in HRV among time using short time Fourier transform (STFT). We expected to get further understanding of neonate by discussing the change and the correlation within cry sound parameters and HRV parameters. The frequency HRV analysis shows that during resting, the dominant energy is in VLF band and the LF band is next. There is barely energy in HF band. The respiratory sinus arrhythmia peak, which is commonly seen in adult’s high frequency band in HRV spectrum, is rarely found in neonate’s HRV spectrum. After injection, the VLF band energy changed irregularly and the LF band energy significantly decreased. The HF band energy decreased or not changed a lot. While we transferring energy to normalized units, we found that after injection, the HF band energy is increased and LF band energy decreased relatively. We found a negative correlation between cry sound and HRV parameters.