Antioxidation, antiinflammation and growth inhibition of Helicobacter pylori by aqueous ethanol extract of orange peel and pith

• Main Authors: Jhen, 林臻
• Other Authors: 王進崑
• Format: Others
• Language: zh-TW
• Published: 2010
• Online Access: http://ndltd.ncl.edu.tw/handle/37682500343480636304

碩士 === 中山醫學大學 === 營養學系碩士班 === 98 === Citrus fruits are mass produced in the world. Citrus fruits showed high antioxidation and biological activities, including antiinflammation, anti-cardiovascular disease, anti-cancer, anti-bacteria and so on. Citrus fruits peel contained rich flavonoids, but peel is not edible. Pith between peel and pulp contained rich fiber. The composition and biological activities of the peel fiber was never investigated. In this study, 70% ethanol extract of the peel and pith of Ponkan and Liucheng were used for determining the biological activities and antiinflammation. Results showed that ethanol extract of fruit peel and pith both exhibited antioxidation. In addition, pith inhibited COX-2 protein expression on LPS-induced macrophages (RAW264.7). Extracts of peel and pith could inhibit the growth of Helicobacter pylori. Therefore, together use of citrus fruit pulp and pith could be much helpful to health.