Anti-gliadin IgA antibody in patient with autoimmune disease
碩士 === 中山醫學大學 === 免疫學研究所 === 98 === OBJECTIVE: Celiac disease(CD) is a inflammatory enteropathy induced by gliadin in genetically susceptible individuals. Recent report showed link between CD and other autoimmune disease .The relationship between anti-gliadin antibody and patients with autoi...
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ndltd-TW-098CSMU55430022015-10-28T04:07:06Z http://ndltd.ncl.edu.tw/handle/23775066353615431610 Anti-gliadin IgA antibody in patient with autoimmune disease 抗麩質抗體在自體免疫疾病中之免疫球蛋白A 的表現 Chun-Meng- 張孟君 碩士 中山醫學大學 免疫學研究所 98 OBJECTIVE: Celiac disease(CD) is a inflammatory enteropathy induced by gliadin in genetically susceptible individuals. Recent report showed link between CD and other autoimmune disease .The relationship between anti-gliadin antibody and patients with autoimmune disease were estimated in the study. METHODS: The antigen of gliadin were tested in patients with autoimmune disease by enzyme-linked immusorbent assay(ELISA).The sera sample were consisted of 126 patients with Sjogren’s syndrome(SS),and 84 patients with Systemic lupus erythematosus(SLE),42 patients with Rheumatoid arthritis,42 patients with Diabetes mellitus , 42 patients with Ankylosing spondylitis , 42 patients with Hepatitis C virus and35 patients with Anemia. The 27 serum of health group were also obtained. Results: In analysis of anti-gliadin IgA antibody,12(9.52%)of 126 patient serums with SS,21(25%)of 84 patient serums with SLE,1(2.38%) of 42 patient serums with RA,6(14.3%)of42patient serums withDM,3(8.57%)of 35 patient serums with Anemia, 3(7.1%)of42patient serums with AS, 9(21.43%)of42patient serums with HCV, 1(3.7%) of 27 the health group have antibody reacted with gliadin. Conclusions: Our result shows that the patients with SLE were higher anti-gliadin antibody than patients with other autoimmune disease. The relationship between the patient s with CD and other autoimmune disease should be estimated in the future. 蔡嘉哲 2010 學位論文 ; thesis 37 zh-TW |
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碩士 === 中山醫學大學 === 免疫學研究所 === 98 === OBJECTIVE:
Celiac disease(CD) is a inflammatory enteropathy induced by gliadin in genetically susceptible individuals. Recent report showed link between CD and other autoimmune disease .The relationship between anti-gliadin antibody and patients with autoimmune disease were estimated in the study.
METHODS:
The antigen of gliadin were tested in patients with autoimmune disease by enzyme-linked immusorbent assay(ELISA).The sera sample were consisted of 126 patients with Sjogren’s syndrome(SS),and 84 patients with Systemic lupus erythematosus(SLE),42 patients with Rheumatoid arthritis,42 patients with Diabetes mellitus , 42 patients with Ankylosing spondylitis , 42 patients with Hepatitis C virus and35 patients with Anemia. The 27 serum of health group were also obtained.
Results:
In analysis of anti-gliadin IgA antibody,12(9.52%)of 126 patient serums with SS,21(25%)of 84 patient serums with SLE,1(2.38%) of 42 patient serums with RA,6(14.3%)of42patient serums withDM,3(8.57%)of 35 patient serums with Anemia, 3(7.1%)of42patient serums with AS, 9(21.43%)of42patient serums with HCV, 1(3.7%) of 27 the health group have antibody reacted with gliadin.
Conclusions:
Our result shows that the patients with SLE were higher anti-gliadin antibody than patients with other autoimmune disease.
The relationship between the patient s with CD and other autoimmune disease should be estimated in the future.
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author2 |
蔡嘉哲 |
author_facet |
蔡嘉哲 Chun-Meng- 張孟君 |
author |
Chun-Meng- 張孟君 |
spellingShingle |
Chun-Meng- 張孟君 Anti-gliadin IgA antibody in patient with autoimmune disease |
author_sort |
Chun-Meng- |
title |
Anti-gliadin IgA antibody in patient with autoimmune disease |
title_short |
Anti-gliadin IgA antibody in patient with autoimmune disease |
title_full |
Anti-gliadin IgA antibody in patient with autoimmune disease |
title_fullStr |
Anti-gliadin IgA antibody in patient with autoimmune disease |
title_full_unstemmed |
Anti-gliadin IgA antibody in patient with autoimmune disease |
title_sort |
anti-gliadin iga antibody in patient with autoimmune disease |
publishDate |
2010 |
url |
http://ndltd.ncl.edu.tw/handle/23775066353615431610 |
work_keys_str_mv |
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