Chemical and Bioactive Constituents from the Leaves of Nelumbo nucifera Gaertn cv. Rosa-plena

• Main Authors: Woei-Ling Yang, 楊偉伶
• Other Authors: Shyh-Chyun Yang
• Format: Others
• Language: zh-TW
• Published: 2010
• Online Access: http://ndltd.ncl.edu.tw/handle/65041961831071903741

碩士 === 高雄醫學大學 === 藥學研究所 === 98 === Nelumbo nucifera Gaertn is a perennial aquatic crop grown and consumed throughout Asia. All parts of N. nucifera have been used for various medicinal purposes in oriental medicine. In particular, the leaves are known for diuretic and astringent properties, and are used to treat fever, sweating, and strangury and as a styptic. To further understand the chemotaxonomy of the Nelumbo species, N. nucifera Gaertn cv. Rosa-plena was chosen for phytochemical investigation. However, there are no publications reported concerning the chemical component of this scientific name yet. There are several compounds derived from the leaves of N. nucifera, which include seven aporphines, (-)-nuciferine (1), (-)-nornuciferine (2), (-)-asmilobine (3), (-)-N-methylasimilobine (4), (-)-caaverine (5), (-)-anonaine (6) and (-)-roemerine (7); two oxoaporphines, lysicamine (8) and liriodenine (9); and one dioxoaporphine, cepharadione B (10); and one dehydroaporphine, 7-hydroxydehydronuciferine (11); two steroids, β-sitostenone (12) and stigmasta-4,22-dien-3-one (13); two chlorophylls, pheophytin-a (14) and aristophyll-C (15). Some of the isolated components from Nelumbo also have not been published, including (-)-caaverine (5), lysicamine (8), cepharadione B (10) and 7-hydroxydehydronuciferine (11). The bioactivities of this compounds, including anticancer and antioxidants were thus examined.