Fast detection of local anesthetic levobupivacaine by impedance method on Polypyrrole/single wall carbon nanotubes
碩士 === 靜宜大學 === 應用化學研究所 === 98 === A fast response and recovery time on electrochemical impedance method developed to detect concentrations of the local anesthetic levobupivacaine hydrochloride was implemented, and concentrations of 1 ppm could be detected .Composites of polypyrrole (Ppy) and polyp...
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| Other Authors: | |
| Format: | Others |
| Language: | zh-TW |
| Published: |
2010
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| Online Access: | http://ndltd.ncl.edu.tw/handle/35007594354088116832 |
| Summary: | 碩士 === 靜宜大學 === 應用化學研究所 === 98 === A fast response and recovery time on electrochemical impedance method developed to detect concentrations of the local anesthetic levobupivacaine hydrochloride was implemented, and concentrations of 1 ppm could be detected .Composites of polypyrrole (Ppy) and polypyrrole- single walled carbon nanotubes (Ppy-SWCNTs) were synthesized coated over gold electrodes for sensing studies. The morphology of the composites was characterized by FTIR ,Cyclic Voltammetry ,Scanning Electron Microscope and Transmission Electron Microscope. Various concentrations of Levobupivacaine from 1 to 500 ppm were prepared in DI water and medical injection 0.9 % NaCl solution as the test samples. A 10-kHz frequency was used for the calibration curve, and the short response and recovery time was tested as 5 s and 3 s. The Ppy/SWCNT material showed better linearity than Ppy material and with R2 as 0.9971. Using molecular dynamic simulation studies exothermic adsorption energies and bond lengths have been calculated and explained the fast response time and lower impedance of Ppy/SWCNT than Ppy.
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