Therapeutic effects of interferon-α and cytosine deaminase gene therapy in orthotopic glioma models in animals

Therapeutic effects of interferon-α and cytosine deaminase gene therapy in orthotopic glioma models in animals

碩士 === 國立中正大學 === 分子生物研究所 === 99 === Replication-competent retrovirus (RCR) vectors derived from Murine Leukemia virus and Gibbon apes Leukemia virus have been developed to improve transduction efficiency of traditional retrovirus vectors. The therapeutic efficacies of RCR vectors highly depend on v...

Full description

Bibliographic Details
Main Authors:	Haofang Chang, 張豪方
Other Authors:	Chien-Kuo Tai
Format:	Others
Language:	zh-TW
Published:	2011
Online Access:	http://ndltd.ncl.edu.tw/handle/85896229370403279565

Similar Items

Characteristics and efficacy of cytosine and cytidine deaminase
by: Qusay Chalabi, et al.
Published: (2007-01-01)

The crystal structure of yeast cytosine deaminase and its application in enzyme-prodrug gene therapy.
by: Yi-Hsin Hsu, et al.
Published: (2003)

Gene Therapy with Cytosine Deaminase and Endostatin Fusion Gene Mediated by Endothelial Progenitor Cells in Hepatomas
by: Zhang YL, et al.
Published: (2020-04-01)

Research advances on cytosine deaminase APOBEC1
by: ZHOU Binghan, et al.
Published: (2020-04-01)

The Feasibility of Using Bacterial Cytosine Deaminase Gene as a Positive or Negative Selection Marker in the Retroviral Vector for Gene Therapy
by: Yang, Hsiang-Mei, et al.
Published: (1996)

AID/APOBEC cytosine deaminase induces genome-wide kataegis
by: Lada Artem G, et al.
Published: (2012-12-01)

A cytosine deaminase for programmable single-base RNA editing
by: Abudayyeh, Omar O., et al.
Published: (2020)

RCR vector-mediated suicide genes of cytosine deaminase and thymidine kinase therapy for breast cancer by local activation of prodrugs
by: Yi-ping Luo, et al.
Published: (2009)

Microbial cytosine deaminases and their use in a new kind of cancer chemotherapy
by: Katsuragi, Tohoru
Published: (2009)

Cytosine and adenine deaminase base-editors induce broad and nonspecific changes in gene expression and splicing
by: Jiao Fan, et al.
Published: (2021-07-01)

Effects of Genetically Engineered Stem Cells Expressing Cytosine Deaminase and Interferon-Beta or Carboxyl Esterase on the Growth of LNCaP Prostate Cancer Cells
by: Kyung-Chul Choi, et al.
Published: (2012-09-01)

Retrovirus mediated suicide gene therapy and cytokine modulated immunotherapy for orthotopic glioma
by: Sheng-Che Lin, et al.
Published: (2011)

Inhibition of MEK/ERK Pathway Enhances the Therapeutic Efficacy of Docetaxel and Cytosine Deaminase/5-FC in Triple-negative Breast Cancers
by: Yin-Che Lu, et al.
Published: (2015)

Cancer-Specific Inhibitory Effects of Genetically Engineered Stem Cells Expressing Cytosine Deaminase and Interferon-β Against Choriocarcinoma in Xenografted Metastatic Mouse Models
by: Gyu-Sik Kim, et al.
Published: (2018-02-01)

Selective antitumor effect of neural stem cells expressing cytosine deaminase and interferon-beta against ductal breast cancer cells in cellular and xenograft models
by: Bo-Rim Yi, et al.
Published: (2014-01-01)

In silico evaluation of rare codons and their positions in the structure of cytosine deaminase and substrate docking studies
by: Mojtaba Mortazavi, et al.
Published: (2016-06-01)

CRISPR-mediated base editing in mice using cytosine deaminase base editor 4
by: Salah Adlat, et al.
Published: (2021-07-01)

In silico evaluation of rare codons and their positions in the structure of cytosine deaminase and substrate docking studies
by: Mojtaba Mortazavi, et al.
Published: (2016-06-01)

Antitumor efficacy of cytosine deaminase-armed vaccinia virus plus 5-fluorocytosine in colorectal cancers
by: Yuedi Ding, et al.
Published: (2020-06-01)

Characterization and Cytotoxic Activity of Cytosine Deaminase Enzyme Purified from Locally Isolated Escherichia coli
by: Baghdad Science Journal
Published: (2018-09-01)

Mutation Processes in 293-Based Clones Overexpressing the DNA Cytosine Deaminase APOBEC3B.
by: Monica K Akre, et al.
Published: (2016-01-01)

Effectiveness of the enzyme cytosine deaminase in the free living ciliary organism Tetrahymena pyriformis (Ehrenberg, 1830)
by: Zahraa Bashi, et al.
Published: (2008-09-01)

Characterization of Fusion Protein Composed of Herpes Simplex Virus VP22 Protein and Cytosine Deaminase
by: Chu Mei-Hung, et al.
Published: (2001)

Quantitative Evaluation of Intraventricular Delivery of Therapeutic Neural Stem Cells to Orthotopic Glioma
by: Margarita Gutova, et al.
Published: (2019-02-01)

Imaging Expression of Cytosine Deaminase-Herpes Virus Thymidine Kinase Fusion Gene (CD/TK) Expression with [I]FIAU and PET
by: Trevor Hackman, et al.
Published: (2002-01-01)

Development of a binary positive and negative protein fragment complementation assay using yeast cytosine deaminase
by: Ear, Po Hien
Published: (2016)

Anti-tumor targeting therapy using recombinant fusion proteins (RGD4C-yeast cytosine deaminase series) with 5-fluorocytosine
by: Li-Chen Chen, et al.
Published: (2016)

The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis
by: Gabriel J. Starrett, et al.
Published: (2016-09-01)

Anti-Tumor Therapy Mediated by 5-Fluorocytosine and a Recombinant Fusion Protein Containing human epidermal growth factor and Yeast Cytosine Deaminase
by: Hao-Qun Lin, et al.
Published: (2013)

Human Sulfatase-1 Improves the Effectiveness of Cytosine Deaminase Suicide Gene Therapy with 5-Fluorocytosine Treatment on Hepatocellular Carcinoma Cell Line HepG2 In Vitro and In Vivo
by: Xiao-Ping Yang, et al.
Published: (2015-01-01)

Loss of the abasic site sensor HMCES is synthetic lethal with the activity of the APOBEC3A cytosine deaminase in cancer cells.
by: Josep Biayna, et al.
Published: (2021-03-01)

Replication protein A (RPA) hampers the processive action of APOBEC3G cytosine deaminase on single-stranded DNA.
by: Artem G Lada, et al.
Published: (2011-01-01)

Biological characterizations of Tumor-targeting Fusion Proteins－NGR-Cytosine Deaminase and RGD-hEGF－against Tumor and Angiogenesis
by: Wei-Cheng Juan, et al.
Published: (2015)

Antitumor Efficacy of Intravesical BCG, Gemcitabine, Interferon-α and Interleukin-2 as Mono- or Combination-Therapy for Bladder Cancer in an Orthotopic Tumor Model
by: Zhengwen Xiao, et al.
Published: (2011-01-01)

Sensitivity of MRI tumor biomarkers to VEGFR inhibitor therapy in an orthotopic mouse glioma model.
by: Christian T Farrar, et al.
Published: (2011-03-01)

Evaluation of 188Re-labeled PEGylated nanoliposome as a radionuclide therapeutic agent in an orthotopic glioma-bearing rat model
by: Huang FYJ, et al.
Published: (2015-01-01)

Generation and characterization of a human single-chain fragment variable (scFv) antibody against cytosine deaminase from Yeast
by: Tombesi Marina, et al.
Published: (2008-09-01)

A Retroviral Replicating Vector Encoding Cytosine Deaminase and 5-FC Induces Immune Memory in Metastatic Colorectal Cancer Models
by: Kader Yagiz, et al.
Published: (2018-03-01)

Gene Therapy For Adenosine Deaminase Deficiency: Successes and Limitations
by: Michael Woo
Published: (2020-12-01)

Myeloprotection by Cytidine Deaminase Gene Transfer in Antileukemic Therapy
by: Nico Lachmann, et al.
Published: (2013-03-01)