Effect of operating variables on the surface morphology and bioactivity of anodized titanium in bone repair

• Main Authors: Chin, 黃欽
• Other Authors: 燕敏
• Format: Others
• Language: zh-TW
• Published: 2011
• Online Access: http://ndltd.ncl.edu.tw/handle/90074243362135484307

碩士 === 中山醫學大學 === 口腔材料科學研究所 === 99 === Titanium is a good strength / weight ratio and high biocompatibility of the metal. Via electrochemical process method, we can transform the titanium surface to a layer of titanium dioxide, titanium dioxide is used in many fields, such as photocatalyst, dye-sensitized cells, sunscreen, biocompatible materials, bone repair materials, etc. In Bone repair materials, such as dental implants, the screws of bone repair , artificial hip joint, etc., need titanium / titanium dioxide, this kind of composite material, the main reason is to merger the high mechanical strength of titanium and the bio-compatible of titanium dioxide layer, especially in modification of titanium dioxide, due to the different surface structures on the hard bone growth and bone regeneration has a great influence. In this study, titanium metal surface by anodic oxidation approach, by controlling the voltage, current, temperature, time and electrolyte concentration, made the titanium surface of the titanium dioxide layer become different morphologies. Seeking different morphologies of topography to create a highly biocompatible surface structure used in bone repair materials, it cause the patient after surgery to enhance response capabilities, especially because some of the poor or congenital bone disease osteoporosis, so the surface of bone repair material modification is a necessary process. In the experimental study found that several groups of parameters have a special structure: at 30V/55 ℃ conditions, resulting in long fibrous tissue, every fiber has a size of about 20 ~ 30nm crystalline. In addition, under the conditions at 10V/55 ℃, titanium dioxide surfaces showed similar cross-section of bone tissue structure, and a very high proportion of titanium dioxide crystals. In order to understand whether the treated specimen can induce bony cells attached on the surface better, the specimen after immersion in simulated body fluid (1.3.7 days), in the result of scanning electron microscopy image we can find hydroxyapatite generation, changes and coverage situations. In the field of titanium dioxide research, there is no one studies the temperature of the anodizing electrolyte; one of the basic physical parameters and has great influence, this experiment also found that when the electrolyte temperature rises can effectively improve the surface structure of titanium dioxide more complex and new crystal has generation.