| Summary: | 碩士 === 國立臺灣海洋大學 === 食品科學系 === 99 === The purpose of this study was to find out the optimum condition of producing on high angiotensin converting enzyme inhibitory peptide okara-natto by Taguchi method.The result found that the optimum condition was added 3% vitamin mixture, 5% xylose, 10% yeast extract, 2% salt after 35℃ ferments for 24 hours and has the best ACE inhibitory rate (61.8±1.54%).
The 0 mg/kg/day (blank group), 0.1 g/kg/day (low dose group), and the 1 g/kg/day (high dose group) of the okara-natto aqueous extract was oral administrated to the spontaneously hypertensive rat.After 8 weeks fed, the systolic pressure and the diastolic pressure in high dose group was decreased 13.73±1.82 mmHg and 23.55±6.79 mmHg resperted compared with the control group; but the weight of heart was increased 0.02±0.00% (g) and the weight of liver was decreased 0.06±0.03% (g).As the result, the high ACE inhibitory peptides okara-natto in this study had bioactivity to lower the blood press.
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