| Summary: | 碩士 === 國立臺灣海洋大學 === 機械與機電工程學系 === 99 === Abstract
Microfluidic lenses have important applications, such as: biomedical array of chemical reactions, cell sorting, optical signal detection, and so on. A two-dimensional (2-D) microfluidic lens is formed by 2-D hydrodynamic focusing with a core flow and a sheath flow of high and low refractive indexes respectively. However, such a lens can only focus light in the horizontal plan, but not in vertical plan. This problem can be overcome by 3-D microfluidic lenses.
In this thesis, a computational fluid dynamics software (COMSOL Multiphysics) is used in analyzing microfluidic lenses. In general, a microfluidic lens is a two-phse flow problem, which is difficult due to moving interface of two immiscible fluids. In order to simplify the two-phase flow problem, it is approximated by a convection and diffusion problem for one fluid. Simulation results show good agreement with experimental results for the lens geometry in the horizontal (X-Y) plane. However, the lens geometry in the vertical (X-Z) plane has great discrepancy with experical results, which can be attributed to surface tension between interface of two-phase flow. In summary, this approach can be a useful tool in the design of microfluidic lenses.
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