High Stability and Antibacterial Activity of Silver Nanoparticles Supported by Clay Silicate Platelets

• Main Authors: Yu-Ting Yen, 顏于婷
• Other Authors: 林江珍
• Format: Others
• Language: en_US
• Published: 2011
• Online Access: http://ndltd.ncl.edu.tw/handle/75142953626877862556

碩士 === 國立臺灣大學 === 高分子科學與工程學研究所 === 99 === A new class of nanohybrids were synthesized by complexing silver nanoparticles (AgNPs) with clay silicate platelets and evaluated for antibacterial activities. Various silver particle sizes in the range of 3.8 to 35 nm diameter were tailored by using nanoscale silicate platelets (NSP) at 1.0 nm thickness as supports. High stability and antibacterial activity were achieved. The efficacy of AgNPs on NSP was highly dependent on the silver particle size in the tests of controlling dermal pathogens including Gram-positive and Gram-negative bacteria. Scanning electron microscope had directly observed the adherence of the nanohybrids to the surface of individual bacteria. The role of NSP as surface supports for immobilizing AgNPs was elucidated by varying the AgNP/NSP weight ratio and testing for their differences in antibacterial efficacy. It is concluded that that hybridization of AgNPs on NSP surface allows the enhancement of AgNP activities and mitigation of their adversary effects on cells.