| Summary: | 碩士 === 東海大學 === 化學工程與材料工程學系 === 99 === Since hitting the market at 1969, acrylic bone cement has become one of the most important biomedical materials at present. The commercial products are usually composed of a solid PMMA powder, and a liquid MMA monomer. Other additives include radiopaques, initiators, stabilizers, accelerators, etc. During the application, PMMA powders are first dissolved in MMA monomer to form the dough, and the monomer is subsequently polymerized to the final solid phase. However, large amount of reaction heat released raises the system temperature. The high temperature could not only damage the adjacent tissues, but also limit types of antibiotics from being used. After replacing the MMA monomer with n-BMA, we were able to lower the system temperature to a safe standard. However, the incompatibility between n-BMA and PMMA reduced the conversion of n-BMA, which further weakened the mechanical properties of the cement. PMMA/PBMA copolymer was synthesized using a surfactantless emulsion polymerization scheme to improve the compatibility.
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