| Summary: | 碩士 === 中山醫學大學 === 營養學研究所 === 100 === Probiotics can promote health by improving the intestinal flora. Xylooligosaccharides is one kind of prebiotics, which can selectively promote the growth of probiotics. This study was conducted to investigate the effect of ingested combination of xylooligosaccharides and probiotics on the human intestinal flora. 37 healthy adults aged 22 to 58 were randomized into two groups. Formula A (n=19), daily ingestion of 2 packs of sample (4.2 g per pack), containing Lactobacillus acidophilus, Bacillus coagulans and xylooligosaccharides(XOS). Formula B, The placebo group (n=18), daily ingestion of 2 packs of placebo (without probiotics and prebiotics). The total experimental duration of this study was seven weeks. One week before experiment was run-in period. Four weeks of continuous ingestion of formula A or formula B were administration period. Two weeks after administration were follow-up period. The total aerobic bacteria, Bifidobacterium spp., Lactobacillus spp., E. coil, and Clostridium perfringens were examined every week. Results indicated that four weeks of administration of formula A significantly increased the colony counts of gastrointestinal Bifidobacteria spp and Lactobacillus spp (p<0.05), decreased the clostridium perfringens and E.coli (p<0.05). The use of formula B did not affect the intestinal flora.
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