| Summary: | 碩士 === 輔仁大學 === 公共衛生學系碩士班 === 100 === Abstract
Bisphenol A (BPA) has a similar effect of estrogen. It has been widely used in the production of plastics and plasticizers. BPA might easily release from plastic materials by heating or contacting acid or alkali. BPA can be concentrated and accumulated in the organisms. Therefore, humans might be exposed via contaminated foods intake. This study aimed to develop a stable and reliable method to analyze the BPA concentration of daily food and canned food.
Acetonitrile was applied to dissolve the grinded food sample. The concentrated acetonitrile solution was extracted by the saturated hexane/acetonitrile solution. The residues were then eluted by hexane and acetone solution (7:3, v/v) through a florisil cartridge. The final purified samples were quantified by high-performance liquid chromatograph/fluorescence detector (HPLC/FD).
This study investigated 23 types of foods in Taiwan (n=267). The results indicated that salmon contained the highest amount of BPA , with the concentration of 550.20±673.13 ng/g. The BPA concentration of beef was 419.26±361.73 ng/g, which was the second high. Vegetables, fruits, and the other foods contained lower BPA. All BPA concentrations of investigated foods were significantly different (p<0.05). The canned peanut with an average concentration, 893.86±246.19 ng/g was the highest BPA content among the investigated canned foods. The BPA concentrations of canned corns and canned meats were 196.08±29.95 ng/g and 135.70±73.57 ng/g respectively. The BPA concentrations of all canned foods were significantly different (p<0.05).
This study found that the BPA concentrations in high-fat content foods, such as fish, meat, and canned peanuts were high. To estimate the BPA intake via daily food consumptions of Taiwan adults, a questionnaire regarding the daily food consumptions was distributed randomly in northern, middle, southern Taiwan.In total, 142 copies of questionnaire were returned. The estimations of BPA intake by the questionnaire and the food BPA content showed no differences between females and males (p≥0.05). The BPA intake of the residents in southern Taiwan were significantly higher than those in northern and middle Taiwan (p<0.05). In average, the daily BPA intake via food exposure was 24.06 μg/day for a Taiwan adult.
In summary, bisphenol A exsits in most of the daily food of Taiwan with a detective rate of 97%(259/267). Both BPA intakes and BPA concentration in food was higher than those of other countries. In Taiwan, people intake 5 times high of than the New Zealanders do. Therefore, the bisphenol A in food packaging, food containers and epoxy coating cans should be regulated or replaced by alternative materials.
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