Development of the Disposable High Flow-rate Check-Valve-like Micropump

• Main Authors: Hung-Nien Lai, 賴宏年
• Other Authors: Jr-Lung Lin
• Format: Others
• Language: zh-TW
• Published: 2013
• Online Access: http://ndltd.ncl.edu.tw/handle/64710544528351198715

碩士 === 義守大學 === 機械與自動化工程學系碩士在職專班 === 101 === An infusion pump infuses fluids, medication or nutrients into a patient's circulatory system. Typically, infusion type can be cataloged as continuous infusion (small infusion rate), intermittent infusion (high infusion rate), patient-controlled analgesia (PCA) and parenteral nutrition (PN). Infusion pumps can administer fluids in ways that would be impractically expensive or unreliable if performed manually by nursing staff. Currently, micromachining technology incorporated with bio technology has provided a means to miniaturize microfluidic applications. If we can apply the Bio-MEMS technology to fabricate the infusion pumps, the high-though product will reduce the fabricated cost. In this study, we want to design as well as fabricate a disposal and portable high-through micropump. For the disposable purposed, a kind of polymer-PDMS (polydimethylsiloxane) is chosen, and its flexible material property is also excellent to form the movable membrane of the micro-actuator. Moreover, the new design of the micropump exhibits the functions of an actuation and check-valves in the same PDMS membrane. It is not only to reduce the complex fabrication of the valves, but also to decrease the fluids leakage. However, the deformation characteristics of pneumatic flexible polymer membranes, i.e., the actuated mechanism cannot have been successfully demonstrated in the previous researches. Therefore, the numerical simulation was employed to investigate the shear-strain mechanism and to identify how the deformed behaviors affected by the different operating parameters. Next, the optimal design was facilitated to fabricate the proposed micropump. Finally, the micropump was experimentally investigated for the pumping rate. The flow-rate was achieved as higher as the 12.6 c.c./min. We hope the system provide an application of the drug and nutrition infusion in the future.