| Summary: | 碩士 === 高雄醫學大學 === 口腔衛生科學研究所碩士在職專班 === 101 === Objectives: Our aims were to assess the association between the number of tooth lost, community periodontal index (CPI), and the status of HbA1cHbA1c control.
Methods: A cross-sectional study design was applied in this study. Participants were recruited from a hospital center of health examination located at Kaohsiung city. After the inform consent was obtained, a standardized structure questionnaire was used to collect the demographic data and results of biochemistry test. Oral health examinations were completed by two well-trained dentists. Further to confirm the reduction in HbA1cHbA1c after the periodontal treatment, a retrospective analysis using the electronic hospital records was applied to determine the reduction in plasma HbA1cHbA1c% after periodontal treatment.
Results: A total of 388 participants were recruited into this study. The mean age was 52.5 ± 12.4 years old. There were 101self-reported diabetic patients and 287 controls. The chi-square test showed that the variables of age>55 years old, educational level≦12 years, community periodontal index (CPI) ≧3, number of tooth loss > 4, ALT > 40 IU/L, triglyceride > 150 ( mg/dL ), HbA1cHbA1c > 7％, and AST > 42 IU/L were significant correlated with self-reported diabetics. The similar significant findings were also found between HbA1cHbA1c > 7%, CPI ≧3 and these variables. Multivariate logistic regession analysis showed that the elevation in variables of age (>55vs.≦55 years old) (aOR=2.2，95%CI=1.1-4.3), educational level (≧12 vs.<12 year) (aOR =9.5，95%CI=2.6-34.3), CPI (≧3 vs.<3) (aOR =19.6，95%CI=5.5-70.3), number of tooth lost (>4 vs.≦4)(aOR=6.2，95%CI=2.7-14.3), and triglyceride (>150 vs.≦150 IU/L) (aOR=3.6，95%CI=1.7-7.5) were all significant associated with HbA1cHbA1c>7%。Multivariate logistic regression analysis also indicated that number of teeth lost > 4, abnormal lipid profiles, and HbA1cHbA1c>7% were risk factors for the CPI≧3. A retrospective data analysis in electronic medical records showed that HbA1cHbA1c% value was decreased after the periodontal treatment ( 7.76 ± 1.72 vs.7.45 ± 1.67, p<0.03 ).
Conclusions: We suggested that CPI ≧ 3 and number of tooth lost > 4 can contribute to the HbA1cHbA1c>7% in diabetics. A retrospective analysis confirmed that periodontal treatment could improve the reduction in HbA1cHbA1c% of diabetic patients.
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