Design and Fabrication of a Multipoint pH and Temperature Recording Probe for Real-Time Heart Muscle Monitoring

碩士 === 國立交通大學 === 電子研究所 === 101 === This thesis present a silicon micromachined probe integrated with three Cu-based resistance temperature detectors, three iridium oxide (IrOx)/AgCl pH meters and a PET flexible board as electric interconnect for heart muscle monitoring. The probe exhibits good line...

Full description

Bibliographic Details
Main Authors: Fan, Yang-Tzung, 范揚宗
Other Authors: Cheng, Tu-Ting
Format: Others
Language:en_US
Published: 2012
Online Access:http://ndltd.ncl.edu.tw/handle/56875163959040010537
Description
Summary:碩士 === 國立交通大學 === 電子研究所 === 101 === This thesis present a silicon micromachined probe integrated with three Cu-based resistance temperature detectors, three iridium oxide (IrOx)/AgCl pH meters and a PET flexible board as electric interconnect for heart muscle monitoring. The probe exhibits good linearity 98% at least and sensitivity -52.75mV/pH and 0.0259Ω/°C for pH and temperature sensing, respectively. The probe has been utilized for the pH and temperature detection at different depths of a frozen pig heart defrosting at room temperature for testing its feasibility for heart muscle monitoring application. In the measurement, the change of pH values with time shows the quality of testing pig heart starting with a low pH value resulted by myocardial hypoxia, the increase of pH value caused by the glycogen decomposition and drastically decrease of the pH value due to germs breeding at last. On the other hand, it was found that there is 3°C difference between the outer and inner surface of the pig heart, which is an important factor for a surgeon to considerate the possible side effects like myocardial necrosis on the heart preservation in open heart surgery.