Generation of drugs against a HIF-1α-specific deubiquitinase to treat hypoxic tumors and metastasis

碩士 === 國立陽明大學 === 生化暨分子生物研究所 === 101 ===   Tumor hypoxia is associated with malignant biological phenotype including enhanced invasiveness, angiogenesis, migration and metastasis. Therefore, the hypoxic tumor treatment is most important issue during the cancer therapy. Hypoxia inducible factor-1α (H...

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Bibliographic Details
Main Authors: Shu-Wei Yang, 楊書瑋
Other Authors: Kou-Juey Wu
Format: Others
Language:en_US
Published: 2013
Online Access:http://ndltd.ncl.edu.tw/handle/93307989039076605572