Synergistic suppression of IRS-1 expression by ET-1 and cAMP is mediated by AP-2β in 3T3-L1 adipocytes

碩士 === 國立陽明大學 === 生化暨分子生物研究所 === 101 === 【Abstract】 ET-1 is a 21-amino acid polypeptide. infusion of ET-1 into healthy humans and rats was shown to cause insulin resistance. Moreover, ET-1 was shown to inhibit insulin-stimulated glucose uptake in 3T3-L1 adipocytes. β-Adrenergic agonists have been we...

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Bibliographic Details
Main Authors: Pu-Hung Kao, 高浦宏
Other Authors: Jim-C. Fong
Format: Others
Language:zh-TW
Published: 2013
Online Access:http://ndltd.ncl.edu.tw/handle/58846624413528485467