| Summary: | 碩士 === 逢甲大學 === 資訊電機工程碩士在職專班 === 102 === Postural orthostatic tachycardia syndrome (POTS) is characterized by orthostatic tachycardia in the absence of orthostatic hypotension. Patients with POTS may experience dizziness, lightheadedness and instability while standing. The main purpose of this study is to evaluate the clinical significance of standing balance and cerebral blood flow (CBF) response during tilting in POTS with dizziness. A group of 18 subjects: 9 POTS patients who all experienced dizziness and instability, and 9 age and gender-matched healthy volunteers participated in the experiment. Pressure balance (Center of pressure, CoP) and CBF data from Transcranial Doppler (TCD) for 300 seconds were collected and analyzed between supine and standing (or tilting). There was a significant difference in anterior-posterior swing between POTS patients and healthy subjects during standing (CoP =338.4 ± 113.6 vs. 185.6 ± 38.5 units, p=0.003). The study shows that dizziness and instability in POTS while standing may be caused by the increase of anterior-posterior swing and CBF drop. Further research is needed in this area, particularly concerning the mechanisms of interaction between vestibular and autonomic nervous system regarding pressure balance and CBF regulation.
|
|---|
