| Summary: | 碩士 === 高雄醫學大學 === 護理學研究所 === 102 === The 2011 United States Renal Disease Database (USRDS) showed the prevalence of end stage renal disease (ESRD) in Taiwan was second highest in the world. There is a trend of increasing rate in chronic kidney disease (CKD) combined with metabolic syndrome (MS) year by year. Previous studies revealed that MS would worsen the decline of renal function. However, so far there is no study focusing on the association between self-care, population characteristics and risk factors with prognosis among patients of CKD combined with MS. The goal of our study is to predict the important factors associated with the prognosis of CKD, to develop the prevention strategy which may slow the decline of renal function and to delay the entrance of ESRD.
This was a retrospective cohort study. We enrolled total 465 patients in CKD stage 3 under the nationwide CKD Preventive Project with multidisciplinary care program at a tertiary medical center in Southern Taiwan. From chart review we investigated the association between self-care, population characteristics and risk factors with prognosis among patients of CKD combined with or without MS. Furthermore, we found the main determining factors effecting outcome by statistics analysis including t-test, Chia-Square and Kaplan-Meier survival estimate.
The results showed CKD with MS, young aged, irregular blood pressure monitor were significantly associated with outcome of ESRD. The hazard ratio for ESRD among CKD with MS was 7.31 compared with CKD without MS. In conclusion, we should pay more attention to identify the risk factors of MS among CKD patients and educate for the importance of home blood pressure check to improve the understanding, detection and management of CKD with MS.
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