Role of galectin-1 in the pathogenesis of chronic obstructive pulmonary disease
碩士 === 國立成功大學 === 微生物及免疫學研究所 === 102 === Our researches focus on investigating the association between galectin-1 and chronic obstructive pulmonary disease (COPD), and the main findings include: 1. galectin-1 may play a protective role in CS-induced COPD through its anti-inflammatory activity, 2. p...
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ndltd-TW-102NCKU53800622015-10-14T00:12:48Z http://ndltd.ncl.edu.tw/handle/47026563120324477723 Role of galectin-1 in the pathogenesis of chronic obstructive pulmonary disease 半乳糖凝集素-1在慢性阻塞性肺病的病理生理學角色 Chung-TengWang 王崇騰 碩士 國立成功大學 微生物及免疫學研究所 102 Our researches focus on investigating the association between galectin-1 and chronic obstructive pulmonary disease (COPD), and the main findings include: 1. galectin-1 may play a protective role in CS-induced COPD through its anti-inflammatory activity, 2. prothymosin α suppresses galectin-1 expression, 3. galectin-1-induced autophagy attenuates ROS-induced cell apoptosis. Collectively, our studies suggest that galectin-1 may play a protective role in CS-induced COPD through anti-inflammatory and anti-apoptotic activities. Our results also reveal that ProT may down-regulate galectin-1 expression and thus lead to COPD, especially upon CS exposure. Ai-Li Shiau 蕭璦莉 2014 學位論文 ; thesis 48 zh-TW |
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碩士 === 國立成功大學 === 微生物及免疫學研究所 === 102 === Our researches focus on investigating the association between galectin-1 and chronic obstructive pulmonary disease (COPD), and the main findings include: 1. galectin-1 may play a protective role in CS-induced COPD through its anti-inflammatory activity, 2. prothymosin α suppresses galectin-1 expression, 3. galectin-1-induced autophagy attenuates ROS-induced cell apoptosis. Collectively, our studies suggest that galectin-1 may play a protective role in CS-induced COPD through anti-inflammatory and anti-apoptotic activities. Our results also reveal that ProT may down-regulate galectin-1 expression and thus lead to COPD, especially upon CS exposure.
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Ai-Li Shiau |
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Ai-Li Shiau Chung-TengWang 王崇騰 |
author |
Chung-TengWang 王崇騰 |
spellingShingle |
Chung-TengWang 王崇騰 Role of galectin-1 in the pathogenesis of chronic obstructive pulmonary disease |
author_sort |
Chung-TengWang |
title |
Role of galectin-1 in the pathogenesis of chronic obstructive pulmonary disease |
title_short |
Role of galectin-1 in the pathogenesis of chronic obstructive pulmonary disease |
title_full |
Role of galectin-1 in the pathogenesis of chronic obstructive pulmonary disease |
title_fullStr |
Role of galectin-1 in the pathogenesis of chronic obstructive pulmonary disease |
title_full_unstemmed |
Role of galectin-1 in the pathogenesis of chronic obstructive pulmonary disease |
title_sort |
role of galectin-1 in the pathogenesis of chronic obstructive pulmonary disease |
publishDate |
2014 |
url |
http://ndltd.ncl.edu.tw/handle/47026563120324477723 |
work_keys_str_mv |
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