Role of PPARs on nifedipine-mediated antiplatelet activity, inhibition of CD40L release and NF-κB activation in human platelets
博士 === 國防醫學院 === 生命科學研究所 === 102 === Objectives: Nifedipine, an L-type calcium channel blocker, is widely used in treating hypertension and coronary heart diseases. Previous study has indicated that nifedipine exert antiplatelet and anti-inflammatory activities, but the underlying mechanism is still...
Main Authors: | Ching -Yu Shih, 施靖瑜 |
---|---|
Other Authors: | Tz-Chong Chou |
Format: | Others |
Language: | en_US |
Published: |
2013
|
Online Access: | http://ndltd.ncl.edu.tw/handle/24985173845728320222 |
Similar Items
-
Mechanisms of Nifedipine-Downregulated CD40L/sCD40L Signaling in Collagen Stimulated Human Platelets.
by: Tso-Hsiao Chen, et al.
Published: (2015-01-01) -
Comparison of the Potency of Pterostilbene with NF-κB Inhibitors in Platelet Activation: Mutual Activation by Akt-NF-κB Signaling in Human Platelets
by: Chih-Wei Hsia, et al.
Published: (2021-07-01) -
CD97/ADGRE5 Inhibits LPS Induced NF-κB Activation through PPAR-γ Upregulation in Macrophages
by: Shuai Wang, et al.
Published: (2016-01-01) -
Aberrant CD40-induced NF-κB activation in human lupus B lymphocytes.
by: Wen Zhang, et al.
Published: (2012-01-01) -
Relationship between Platelet PPARs, cAMP Levels, and P-Selectin Expression: Antiplatelet Activity of Natural Products
by: Eduardo Fuentes, et al.
Published: (2013-01-01)