Studies on Chemical Constituents and Biological Activities of the Rhizome of Alpinia officinarum Hance
碩士 === 國立屏東科技大學 === 生物科技系所 === 102 === Alpinia officinarum Hance. ( Zingiberaceae ) is a perennial herb that was widely cultivated in Guangdong, Guangxi, and Taiwan. A. officinarum is also called Liang zang, Gau liang zang, Fong zang, and Hai lang zang. Previous studies have demonstrated tha...
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ndltd-TW-102NPUS51110062016-12-22T04:18:52Z http://ndltd.ncl.edu.tw/handle/54175530045973864713 Studies on Chemical Constituents and Biological Activities of the Rhizome of Alpinia officinarum Hance 高良薑地下莖化學成分與生物活性之研究 Shih-Han Fu 傅詩涵 碩士 國立屏東科技大學 生物科技系所 102 Alpinia officinarum Hance. ( Zingiberaceae ) is a perennial herb that was widely cultivated in Guangdong, Guangxi, and Taiwan. A. officinarum is also called Liang zang, Gau liang zang, Fong zang, and Hai lang zang. Previous studies have demonstrated that A. officinarum rhizomes contain a lot of chemical substances of flavonoids and diarylheptanoids. with anti-cancer, anti-virus, anti-bacterial, anti-inflammatory, anti-mutagenic and anti-oxidant activities. In this study, the air-dried rhizomes of A. officinarum were extracted with methanol. The MeOH extract was partitioned by ethyl acetate and butanol with water, respectively, to give EtOAc, n-BuOH and water layers. The extract of each layer was subjected to screen biological acitrvities and the result showed that the EtOAc layer of A. officinarum rhizomes have significant anti-oxidant and cytotoxic activities. Furthermore, these fractions from the EtOAc layer were purified by repeated column chromatography, high performance liquid chromatography and recrystallization. To obtain 23 compounds including one steroid, three flavonoids, one IV monoterpenoid, two sesquiterpenoids, two aromatics and fourteen diarylheptanoids. Their structures were elucidated by spectroscopic analysis including UV, EI-MS and NMR techniques. Chi-I Chang Ming-Hui Liao 張誌益 廖明輝 2013 學位論文 ; thesis 105 zh-TW |
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碩士 === 國立屏東科技大學 === 生物科技系所 === 102 === Alpinia officinarum Hance. ( Zingiberaceae ) is a perennial herb that was widely
cultivated in Guangdong, Guangxi, and Taiwan. A. officinarum is also called Liang zang,
Gau liang zang, Fong zang, and Hai lang zang. Previous studies have demonstrated that A.
officinarum rhizomes contain a lot of chemical substances of flavonoids and
diarylheptanoids. with anti-cancer, anti-virus, anti-bacterial, anti-inflammatory,
anti-mutagenic and anti-oxidant activities.
In this study, the air-dried rhizomes of A. officinarum were extracted with methanol.
The MeOH extract was partitioned by ethyl acetate and butanol with water, respectively, to
give EtOAc, n-BuOH and water layers.
The extract of each layer was subjected to screen biological acitrvities and the result
showed that the EtOAc layer of A. officinarum rhizomes have significant anti-oxidant and
cytotoxic activities. Furthermore, these fractions from the EtOAc layer were purified by
repeated column chromatography, high performance liquid chromatography and
recrystallization. To obtain 23 compounds including one steroid, three flavonoids, one
IV
monoterpenoid, two sesquiterpenoids, two aromatics and fourteen diarylheptanoids. Their
structures were elucidated by spectroscopic analysis including UV, EI-MS and NMR
techniques.
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author2 |
Chi-I Chang |
author_facet |
Chi-I Chang Shih-Han Fu 傅詩涵 |
author |
Shih-Han Fu 傅詩涵 |
spellingShingle |
Shih-Han Fu 傅詩涵 Studies on Chemical Constituents and Biological Activities of the Rhizome of Alpinia officinarum Hance |
author_sort |
Shih-Han Fu |
title |
Studies on Chemical Constituents and Biological Activities of the Rhizome of Alpinia officinarum Hance |
title_short |
Studies on Chemical Constituents and Biological Activities of the Rhizome of Alpinia officinarum Hance |
title_full |
Studies on Chemical Constituents and Biological Activities of the Rhizome of Alpinia officinarum Hance |
title_fullStr |
Studies on Chemical Constituents and Biological Activities of the Rhizome of Alpinia officinarum Hance |
title_full_unstemmed |
Studies on Chemical Constituents and Biological Activities of the Rhizome of Alpinia officinarum Hance |
title_sort |
studies on chemical constituents and biological activities of the rhizome of alpinia officinarum hance |
publishDate |
2013 |
url |
http://ndltd.ncl.edu.tw/handle/54175530045973864713 |
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