| Summary: | 碩士 === 國立臺灣大學 === 護理學研究所 === 102 === After receiving stem cell transplantation, leukemia patients went through a high- dose chemotherapy conditioning protocol, polypharmacy, and graft-versus-host-disease (GVHD) and had experienced changes of body function and image. Moreover, these changes may affect their quality of life. The purpose of this study was to investigate the relationships among demographic characteristics of stem cell transplantation, conditioning protocol before stem cell transplantation, complications and symptoms after stem cell transplantation, body image, and quality of life. A descriptive, cross-sectional, correlational design was used to recruit leukemia patients who have done allogeneic stem cell transplantation from post-transplantation and hematology outpatient clinics in a stem cell transplantation medical center in northern Taiwan. Instruments used for structured questionnaire data collection were Multidimensional Body-self Relations Questionnaire-Appearance Scale (MBSRQ-AS), the traditional Chinese version of The Functional Assessment of Cancer Therapy- Bone Marrow Transplant version 4 (FACT-BMT), and demographic questionnaire. There were 84 valid samples in this study. The data were analyzed by SPSS 20.0 window and descriptive statistic, t test, ANOVA, Spearman rank correlation, and linear regression analysis. The major findings of this study were as follow: An average of MBSRQ-AS total score were 100.35±13.07, and the mean of patients’ body image were not very satisfied . An average of FACT-BMT total score were 103.37±23.9, and the mean of patients’ quality of life were between middle level and upper level. In order to identify the essential predictors of FACT-BMT, stepwise regression analysis was used in this study. The predictors include MBSRQ-AS total score, age, changes of hair, and months after transplantation. As a result, the total amount of (R2) could explain to 46.2%.
Result: Body image change is a predictor of quality of life for leukemia patients who have received allogeneic stem cell transplantation. Healthcare providers could provide holistic care before patient discharge, and give long-term follow-up on their body image changes in order to help patients acknowledge their body image changes. Hope that we can help leukemia patients adapt to and promote the quality of life after transplantation.
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